AREG

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→ activates EGFR (paracrine)[1]

References

  1. ↑ Laura Ciarloni; Sonia Mallepell; Cathrin Brisken."Amphiregulin is an essential mediator of estrogen receptor α function in mammary gland development".
    In fact, we find that estrogens induce amphiregulin through the ERα and require amphiregulin to induce proliferation of the mammary epithelium.
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