EGFR

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→ facilitates Breast Ductal Lengthening[1]

References

  1. ↑ Laura Ciarloni; Sonia Mallepell; Cathrin Brisken."Amphiregulin is an essential mediator of estrogen receptor α function in mammary gland development".
    In fact, we find that estrogens induce amphiregulin through the ERα and require amphiregulin to induce proliferation of the mammary epithelium.

→ activates PI3K (intracellular)

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